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Study record managers: refer to the Data Element Definitions if submitting registration or information. The purpose of this study is to test the good and bad effects of the study drugs bortezomib and vorinostat when they are given in combination with chemotherapy commonly used to treat acute lymphoblastic leukemia ALL in infants. For example, adding these drugs could kale the of leukemia cells, but it could also cause additional side effects. Bortezomib and vorinostat have been approved by the US Food and Drug Administration FDA to treat other cancers springfield mistress needs to be teased adults, but they have not been approved for treating children with leukemia.

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